Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H 2 S) signaling, report researchers from Japan. Heme binding promotes the reaction of H 2 S with the transcription ...

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

Researchers have found that certain bacteria carry a naturally occurring system, built from repurposed CRISPR components, that switches genes on rather than cutting or silencing DNA. The discovery, ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression. Scientists have now developed a way to silence that cellular noise, ...

Tuberculosis bacteria. Computer artwork of Mycobacterium tuberculosis bacteria, the Gram- positive rod-shaped bacteria which cause the disease tuberculosis. Life is governed by tiers of gene ...

A new technique shows DNA binding domains are not central to transcription factor targeting in human cells, unlike in ...

A research team led by Universitat Autònoma de Barcelona (UAB) researcher David Reverter has discovered the molecular mechanism that describes in detail the process regulating cell division in ...

Just like us, bacteria are under constant threat of infection by viruses (called phages). We’ve found that many bacteria are armed with sophisticated viral defence systems powered by reverse ...

E. coli divides faster than it can replicate its genome, while simultaneously expressing its genes. Scientists recently revealed the intricate molecular coordination that makes this possible. “It’s as ...

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...