Covering both fundamental and applied science, this collection offers readers insights into the core mechanisms by which cells replicate their genetic material and maintain the epigenetic marks that ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

An enduring mystery of 'lagging strand' DNA replication The DNA replication process is carried out by multiple protein complexes with highly specialized functions, including the unwinding of DNA and ...

Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

Before each cell division, eukaryotic cells must replicate their chromosomes to ensure the accurate transmission of genetic information. Chromosome replication involves more than just DNA duplication; ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

Researchers from the University of Birmingham have uncovered answers that provide the detail to explain two specific DNA repair processes that have long been in question. The publication of two papers ...

Mitochondrial transcription elongation factor maintains the balance between transcription and replication of mitochondrial DNA offering insights into potential treatments for mitochondrial disease and ...