Scientists have long believed that large stretches of our genetic material, known as long noncoding RNAs (lncRNAs), help regulate genes but do not produce proteins. A new study by Stav Zok and ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate ...

T, is one of the most devastating genome-instability disorders known to medicine. Children born with the condition face ...

A virus-built molecular weapon targets DNA with a strange gapped code and may reveal how bacteria acquired the foundations of ...

Determining protein structures requires crystals, but getting proteins to crystallize has long depended on a slow, unpredictable process of trial and error ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

Using DNA, the team directed proteins to assemble into diffraction-quality, intentionally designed crystal structures with atomic-level order. The strategy enabled the scientists to precisely control ...

Replication Protein A (RPA) is the principal single-stranded DNA (ssDNA)-binding complex in eukaryotic cells, orchestrating fundamental processes of DNA replication, repair and recombination. As a ...

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 ...