Substance use disorder (SUD) is an extremely difficult disorder to overcome, and many individuals with SUD return to regular use after repeated attempts to quit. A return to regular drug use can be ...

Drug addiction poses a global public health challenge, with limited therapeutic options and modest efficacy. While clinical observations suggest that social rank plays a crucial role in determining ...

Heroin is an illegal drug that people use for its euphoric effects. However, it can lead to addiction and cause severe side effects and withdrawal symptoms. Treatment for heroin addiction involves ...

Heroin addiction can severely impact a person’s life and the lives of their friends and family. A person experiencing heroin addiction may not wish to discuss the fact that they take heroin with ...

One of the longstanding challenges in drug discovery has been the inability to directly observe whether a compound engages its target in a cellular environment under physiologically relevant ...

Social rank regulates methamphetamine-seeking behavior by modulating the mesocortical and mesolimbic dopamine pathways, and winning experiences can remodel these circuits to suppress drug-seeking. In ...