JunB is a member of the Jun family of proteins that are components of the AP-1 transcription factor complex. AP-1 is involved in cell proliferation and apoptosis. Recent evidence suggests that Hodgkin ...
Mice that lack JunB in epidermal cells are born with normal skin; however, keratinocytes hyperproliferate in vitro and on TPA treatment in vivo. Loss of JunB expression in the epidermis of adult mice ...
Researchers learn how a key transcription factor helps regulate the immune system and could be critical to understanding autoimmune disease and cancer immunosuppression. Our immune systems defend our ...
A specific regulatory protein significantly influences the development of tumor-inducing blood vessels in the bone marrow of blood cancer patients. Using a series of different experiments, the team ...
The simultaneous inhibition of the transcription factors Myc and JunB could represent a pioneering therapeutic option for the treatment of multiple myeloma (MM), the second most common type of blood ...
Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end ...
1) The normal process in which JunB can activate the Interleukin 23 (IL23) receptor gene to make the T Helper 17 cell sensitive to Interleukin 23. This potentially lead to the T Helper 17 cell to turn ...
OIST researchers discovered a target to single out immune system cells responsible for auto-immune diseases such as arthritis or irritable bowel syndrome The immune system is a formidable defense ...
Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end ...
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