The Scientist

Interpreting CRISPR Screens Through Protein-Level Biology

Amanda McQuade and Nathaniel Robichaud discuss how integrated proteomic and transcriptomic profiling can reveal cellular ...
Nature

An in-depth transcriptomic atlas deciphering traditional Chinese medicine mechanisms and disease associations

Transcriptomic profiling of Traditional Chinese Medicine (TCM) perturbations is essential for elucidating the molecular mechanisms of therapeutic interventions. Although data from TCM treatment ...
Nature

Integrated proteomic and single-cell transcriptomic profiling elucidates immunomodulatory effects of L-serine in autism spectrum disorder

Autism spectrum disorder (ASD) is classified as early-emerging developmental divergences distinguished by aberrant interpersonal interactions as well as inflexible, stereotyped activities with no ...
ascopubs.org

Transcriptomic Profiling of Primary Prostate Cancers and Nonlocalized Disease on Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography: A ...

We identified patients from four institutions who underwent PSMA PET/CT scans pretreatment for primary staging or postradical prostatectomy (RP) for suspected recurrence and had Decipher ...
ascopubs.org

Spatial transcriptomic profiling from over 300 leiomyosarcoma samples.

Alliance A092104: A randomized phase 2/3 study of olaparib plus temozolomide versus investigator’s choice for the treatment of patients with advanced uterine leiomyosarcoma after progression on prior ...