New research led by immunologist Ming Li from Sloan Kettering Institute unpacks a century-old mystery of cancer: why cancer cells get energy from glucose via an oxygen-independent process called the ...

A century after Otto Warburg first described the phenomenon where cancer cells undergo glycolysis instead of oxygen respiration—even in oxygen-rich environments—the so-called Warburg effect continues ...

In a recent issue of Nature, the findings of one study made a particularly big splash: how and why cancer cells use energy differently than healthy cells. The research builds on an already ...

Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming. This discovery potentially opens up new avenues ...

Cancer cells maintain their life-style of extremely rapid growth and proliferation thanks to an enzyme called PK-M2 (pyruvate kinase M2) that alters the cells' ability to metabolize glucose -- a ...

One hundred years ago German physician Otto Warburg observed that cancer cells harvest energy from glucose sugar in a strangely inefficient manner: rather than burn it using oxygen, cancer cells do ...

In research published in Cancer Cell, Thomas Burris, Ph.D., chair of pharmacology and physiology at Saint Louis University, has, for the first time, found a way to stop cancer cell growth by targeting ...

Belgian scientists say they’ve made a research breakthrough in the relationship between sugar and cancer. Researchers found yeast with high levels of the sugar known as glucose overstimulated the same ...

It's long been known that cancer cells eat a lot of sugar to stay alive. In fact, where normal, noncancerous cells generate energy from using some sugar and a lot of oxygen, cancerous cells use ...

A new study, led by researchers at the University of Chicago, provides an answer to why cancer cells consume and use nutrients differently than their healthy counterparts and how that difference ...

In mammalian cells, there are two main ways to generate energy in the form of adenosine triphosphate from glucose, oxidative phosphorylation and glycolysis. Oxidative phosphorylation occurs in the ...

Tumor cells rely mainly on glycolysis for energy production even in the presence of sufficient oxygen, a phenomenon termed the Warburg effect, which is the most outstanding characteristic of energy ...