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The microscopic origin of line tension, used in the equilibrium description of liquid drops on flat surfaces, is not well understood. Simulations of water nanodroplets show that structural transitions ...
In this issue, Jiang et al. introduce a proteomic method called LoopID and show that JMJD2 demethylases have a non-catalytic role in promoting enhancer–promoter looping in mouse embryonic stem cells.